NAD+ / 5-Amino-1MQ / MOTS-C Stack
Three compounds in one cartridge: NAD+, 5-Amino-1MQ and MOTS-c. Two of the three are connected through the same pathway. This pen holds 200mg, 50mg and 10mg respectively, 260mg total content, already in solution.
Why it is being studiedA real link. Blocking NNMT leaves more nicotinamide available for NAD+ salvage.
Fixed ratio. All three share one solution, so the proportions cannot be varied.
No combination data. Nothing published tests these three together.
Mostly preclinical research. Human data is limited, and nothing here establishes an effect in people.
Original price was: £750.00.£675.00Current price is: £675.00.
Before you start
Check the batch number on the pen against the certificate of analysis on this page. If they don't match, don't use the pen. Contact us and we'll replace it.
Inspect the solution through the window. It should be clear and free of particles. Copper peptide solutions are blue, and that colour is expected. Cloudiness, discolouration or visible matter means the pen should not be used.
The pen
Each pen arrives pre-filled, in solution, at the concentration on the label. There is nothing to reconstitute, no bacteriostatic water to add and no concentration to calculate.
The dose counter is mechanical. Turning the dial advances it one increment at a time, with an audible click per increment, and the number in the window is the amount set. The counter cannot be turned past the volume remaining.
Pens take standard pen needles, supplied with your order. Fit a fresh one each time and remove it afterwards. Leaving a needle attached lets air into the cartridge and can affect what the counter reads next.
Storage
Refrigerate at 2–8°C on arrival and keep the pen in its carton. Peptides in solution degrade faster in light, and copper peptides faster still.
Do not freeze. Freezing damages peptides in solution and the pen cannot be relied on afterwards, whatever it looks like.
Return the pen to refrigeration between uses once the seal is broken. A cold pen is stiffer to dial, so leaving it out for a few minutes beforehand makes the counter turn more smoothly.
Disposal
Used needles go into a sharps container, not household waste. UK pharmacies and local councils both supply them, and most councils collect full ones on request.
Supplied for laboratory research use only. Not for human or veterinary use, and not a medicine. Nothing on this page describes a protocol, a schedule or an application, and none should be inferred.
Every batch is tested before release
No batch reaches our shelves without a report from an independent laboratory. Testing is done by a third party with no commercial interest in the result, not by us and not by the manufacturer.
What the certificate shows
Identity, confirming the compound is what the label says it is. Purity, measured by high-performance liquid chromatography and reported as a percentage. The date of testing and the batch number the result applies to.
How to check it yourself
Every pen carries a batch number, and the certificate on this page carries the same number. If the two don't match, something has gone wrong in our dispatch and we want to hear about it. We'll replace the pen.
Certificates are published as the laboratory issued them. We don't retype results, summarise them or crop the report.
Cold chain
Stock is held refrigerated and ships in insulated packaging with a cold pack. Orders are dispatched so they travel over the shortest practical window rather than sitting in a depot over a weekend.
If a pen arrives damaged, warm, or not matching its certificate, contact us within 48 hours of delivery and we'll replace it.
Why these three together?
NAD+ and 5-Amino-1MQ connect through one pathway: the second blocks an enzyme that drains the precursor the cell uses to make the first. MOTS-c is there because it belongs to the same field of research, not because it shares that pathway.
Can the three be dialled separately?
No. They share one solution at a fixed ratio, so the counter moves all three together. Separate pens are the way to vary them independently.
Why is the total content so much higher than other pens?
Because NAD+ and 5-Amino-1MQ are not signalling peptides and are studied at much larger amounts. Comparing milligram totals across different kinds of molecule is not meaningful.
Is this prohibited in sport?
It is not named on the World Anti-Doping Agency prohibited list, but WADA also bans substances with no current approval for human therapeutic use under S0. Check the current list yourself if you are tested.
Why is the solution clear rather than blue?
Blue solutions in our range are the copper complexes, GHK-Cu and AHK-Cu. This one in solution is clear. Cloudiness or visible particles mean the pen should not be used.
How many doses are in a 260mg pen?
That depends entirely on the increment you dial, so there is no single answer. The counter shows what is set and the pen cannot be turned past the volume remaining.
Store at 2–8°C
Refrigerate on arrival and keep the pen in its carton, away from light.
Cold-chain shipped
Insulated packaging with a cold pack, in a plain outer box with no reference to the contents.
Never freeze
Freezing damages peptides held in solution. A frozen pen cannot be relied on afterwards.
Third-party tested
Every batch tested by an independent laboratory for identity and purity by HPLC.
Batch traceable
The batch number printed on the pen matches the number on its certificate.
Certificate on the page
Published exactly as the laboratory issued it. Not summarised, not on request.
Product Description
A combination pen holding three compounds of different classes in one solution: NAD+, a coenzyme; 5-Amino-1MQ, a synthetic small molecule; and MOTS-c, a sixteen amino acid mitochondrial-derived peptide. The certificate reports each against the reference appropriate to its class.
All three are already in solution at stated concentrations, so there is no mixing step and no need to combine separate preparations. One pen, one mechanical dose counter, standard pen needle fitting.
Each compound is tested separately by an independent laboratory, and the combined batch is tested again after filling. The certificate of analysis on this page records identity and purity for every compound in the pen, with the test date and a batch number matching the pen.
Store refrigerated at 2–8°C and keep the pen in its carton, away from light. Do not freeze. Once the seal is broken, keep the pen refrigerated between uses and replace the cap after each use.
Ships in insulated packaging with a cold pack, in a plain outer box with no reference to the contents. Supplied for laboratory research use only. Not for human or veterinary use, and not a medicine.
How does it work
Two of these three connect through one pathway. Cells rebuild NAD+ from nicotinamide through the salvage pathway. NNMT methylates nicotinamide and diverts it away from that route, and 5-Amino-1MQ inhibits NNMT. Supplying NAD+ while inhibiting the enzyme that drains its precursor is the stated rationale for pairing them.
MOTS-c is the odd one out. It is a mitochondrial peptide that signals through AMPK and is not part of that pathway, included because it appears in the same metabolic research. No published work tests these three as a combination.
The published base here is small and much of it is preclinical. Nothing in it establishes an effect in people, and we make no claim that it does.
What’s included
- One pre-filled NAD+ / 5-Amino-1MQ / MOTS-C pen, 200mg / 50mg / 10mg total content, supplied in solution
- Pen needles
- Storage and handling card
- Certificate of analysis, published on this page
- Insulated packaging with a cold pack
Specifications
- SKU
- NW-P-NADMQMOTS-200-50-10
- Format
- Pre-filled pen, in solution
- Total content
- 200mg / 50mg / 10mg
- Compounds
- NAD+, 5-Amino-1MQ, MOTS-c
- Storage
- Refrigerate at 2–8°C
- Batch number
- NW-NAMM-261008-A
Related Products
