NAD+ Pen
A coenzyme rather than a peptide, present in every cell and central to how cells move electrons during energy metabolism. Also the substrate consumed by sirtuins and PARP enzymes. Available in 500mg and 1000mg pens, already in solution.
Why it is being studiedRedox carrier. Carries electrons in the reactions that release energy from fuel.
Enzyme substrate. Consumed rather than recycled by sirtuins, PARPs and CD38.
Route of delivery. Whether administered NAD+ enters cells intact is an open question.
Mostly preclinical research. Human data is limited, and nothing here establishes an effect in people.
£399.00 – £630.00Price range: £399.00 through £630.00
Before you start
Check the batch number on the pen against the certificate of analysis on this page. If they don't match, don't use the pen. Contact us and we'll replace it.
Inspect the solution through the window. It should be clear and free of particles. Copper peptide solutions are blue, and that colour is expected. Cloudiness, discolouration or visible matter means the pen should not be used.
The pen
Each pen arrives pre-filled, in solution, at the concentration on the label. There is nothing to reconstitute, no bacteriostatic water to add and no concentration to calculate.
The dose counter is mechanical. Turning the dial advances it one increment at a time, with an audible click per increment, and the number in the window is the amount set. The counter cannot be turned past the volume remaining.
Pens take standard pen needles, supplied with your order. Fit a fresh one each time and remove it afterwards. Leaving a needle attached lets air into the cartridge and can affect what the counter reads next.
Storage
Refrigerate at 2–8°C on arrival and keep the pen in its carton. Peptides in solution degrade faster in light, and copper peptides faster still.
Do not freeze. Freezing damages peptides in solution and the pen cannot be relied on afterwards, whatever it looks like.
Return the pen to refrigeration between uses once the seal is broken. A cold pen is stiffer to dial, so leaving it out for a few minutes beforehand makes the counter turn more smoothly.
Disposal
Used needles go into a sharps container, not household waste. UK pharmacies and local councils both supply them, and most councils collect full ones on request.
Supplied for laboratory research use only. Not for human or veterinary use, and not a medicine. Nothing on this page describes a protocol, a schedule or an application, and none should be inferred.
Every batch is tested before release
No batch reaches our shelves without a report from an independent laboratory. Testing is done by a third party with no commercial interest in the result, not by us and not by the manufacturer.
What the certificate shows
Identity, confirming the compound is what the label says it is. Purity, measured by high-performance liquid chromatography and reported as a percentage. The date of testing and the batch number the result applies to.
How to check it yourself
Every pen carries a batch number, and the certificate on this page carries the same number. If the two don't match, something has gone wrong in our dispatch and we want to hear about it. We'll replace the pen.
Certificates are published as the laboratory issued them. We don't retype results, summarise them or crop the report.
Cold chain
Stock is held refrigerated and ships in insulated packaging with a cold pack. Orders are dispatched so they travel over the shortest practical window rather than sitting in a depot over a weekend.
If a pen arrives damaged, warm, or not matching its certificate, contact us within 48 hours of delivery and we'll replace it.
Is NAD+ a peptide?
No. It is a dinucleotide coenzyme built from two nucleotides, not from amino acids. It sits in this range because it belongs to the same metabolic research, not because it is the same kind of molecule.
How does this differ from NMN or NR?
Those are smaller precursors the cell converts into NAD+. This is the coenzyme itself. The precursors have more human trial data behind them, largely because their size makes absorption a simpler question.
What is the difference between the 500mg and 1000mg pens?
Only the amount in the cartridge. Same compound, same solution, same certificate format. The larger pen holds twice as much.
Is this prohibited in sport?
It is not named on the World Anti-Doping Agency prohibited list, but WADA also bans substances with no current approval for human therapeutic use under S0. Check the current list yourself if you are tested.
Why is the solution clear rather than blue?
Blue solutions in our range are the copper complexes, GHK-Cu and AHK-Cu. This one in solution is clear. Cloudiness or visible particles mean the pen should not be used.
How many doses are in a 500mg or 1000mg pen?
That depends entirely on the increment you dial, so there is no single answer. The counter shows what is set and the pen cannot be turned past the volume remaining.
Store at 2–8°C
Refrigerate on arrival and keep the pen in its carton, away from light.
Cold-chain shipped
Insulated packaging with a cold pack, in a plain outer box with no reference to the contents.
Never freeze
Freezing damages peptides held in solution. A frozen pen cannot be relied on afterwards.
Third-party tested
Every batch tested by an independent laboratory for identity and purity by HPLC.
Batch traceable
The batch number printed on the pen matches the number on its certificate.
Certificate on the page
Published exactly as the laboratory issued it. Not summarised, not on request.
Product Description
NAD+ is nicotinamide adenine dinucleotide, a coenzyme rather than a peptide. It is listed alongside the peptide range because it is supplied and handled the same way, but it is a different class of compound and the certificate reflects that: purity is reported against a small-molecule reference rather than a peptide sequence.
There is nothing to reconstitute. The compound arrives already dissolved at a known concentration, so there is no bacteriostatic water to add, no vial to swirl and no concentration to calculate. The dose is set on a mechanical counter that clicks as it turns, and the pen takes standard pen needles.
Every batch is tested by an independent laboratory before release. The certificate of analysis for this batch is published on this page and records identity, purity by HPLC and the date of testing. The batch number on the pen matches the batch number on the certificate.
Refrigerate at 2–8°C on arrival and keep the pen in its carton. NAD+ in solution is sensitive to both light and warmth, so return the pen to the fridge promptly after each use. Do not freeze.
Ships in insulated packaging with a cold pack, in a plain outer box with no reference to the contents. Supplied for laboratory research use only. Not for human or veterinary use, and not a medicine.
How does it work
NAD+ does two different jobs. As a redox carrier it shuttles electrons through the reactions that release energy from fuel, cycling between its oxidised and reduced forms without being used up. Separately it is a substrate: sirtuins, PARP enzymes and CD38 cleave it, so that pool has to be continuously rebuilt through the salvage pathway.
The honest complication with administering NAD+ itself is that it is a large, charged molecule. Much of the published work on raising cellular levels uses smaller precursors instead, on the basis that those cross membranes more readily. Whether intact NAD+ reaches the inside of cells, or is broken down first and rebuilt, is not settled.
That is the mechanism as described in the literature. How much of it translates beyond the laboratory is not established, and we make no claim that it does.
What’s included
- One pre-filled NAD+ pen, 500mg or 1000mg depending on the option selected total content, supplied in solution
- Pen needles
- Storage and handling card
- Certificate of analysis, published on this page
- Insulated packaging with a cold pack
Specifications
- SKU
- NW-P-NAD
- Format
- Pre-filled pen, in solution
- Compounds
- NAD+ (nicotinamide adenine dinucleotide)
- Storage
- Refrigerate at 2–8°C
- Batch number
- NW-NAD-260810-A
