TB-500 Pen

How it works Certificate on every batch

What it is

A synthetic peptide copying the active section of thymosin beta-4. A seven amino acid chain, not the full protein. This pen holds 5mg, already in solution.

Why it is being studied

Tissue repair. Animal models of skin, corneal and cardiac injury.

Cell migration. Thymosin beta-4 binds actin, which cells use to change shape.

Inflammation. A smaller body of work. Findings are mixed.

Good to know

5mg pen store 2–8°C needle included research use only

Mostly preclinical research. Human data is limited, and nothing here establishes an effect in people.

Original price was: £300.00.Current price is: £270.00.

Certificate of analysis Batch NW-TB5-260918-A · published as issued View →

How to Use

Before you start
Check the batch number on the pen against the certificate of analysis on this page. If they don't match, don't use the pen. Contact us and we'll replace it.

Inspect the solution through the window. It should be clear and free of particles. Copper peptide solutions are blue, and that colour is expected. Cloudiness, discolouration or visible matter means the pen should not be used.

The pen
Each pen arrives pre-filled, in solution, at the concentration on the label. There is nothing to reconstitute, no bacteriostatic water to add and no concentration to calculate.

The dose counter is mechanical. Turning the dial advances it one increment at a time, with an audible click per increment, and the number in the window is the amount set. The counter cannot be turned past the volume remaining.

Pens take standard pen needles, supplied with your order. Fit a fresh one each time and remove it afterwards. Leaving a needle attached lets air into the cartridge and can affect what the counter reads next.

Storage
Refrigerate at 2–8°C on arrival and keep the pen in its carton. Peptides in solution degrade faster in light, and copper peptides faster still.

Do not freeze. Freezing damages peptides in solution and the pen cannot be relied on afterwards, whatever it looks like.

Return the pen to refrigeration between uses once the seal is broken. A cold pen is stiffer to dial, so leaving it out for a few minutes beforehand makes the counter turn more smoothly.

Disposal
Used needles go into a sharps container, not household waste. UK pharmacies and local councils both supply them, and most councils collect full ones on request.

Supplied for laboratory research use only. Not for human or veterinary use, and not a medicine. Nothing on this page describes a protocol, a schedule or an application, and none should be inferred.

Testing & Quality Standards

Every batch is tested before release
No batch reaches our shelves without a report from an independent laboratory. Testing is done by a third party with no commercial interest in the result, not by us and not by the manufacturer.

What the certificate shows
Identity, confirming the compound is what the label says it is. Purity, measured by high-performance liquid chromatography and reported as a percentage. The date of testing and the batch number the result applies to.

How to check it yourself
Every pen carries a batch number, and the certificate on this page carries the same number. If the two don't match, something has gone wrong in our dispatch and we want to hear about it. We'll replace the pen.

Certificates are published as the laboratory issued them. We don't retype results, summarise them or crop the report.

Cold chain
Stock is held refrigerated and ships in insulated packaging with a cold pack. Orders are dispatched so they travel over the shortest practical window rather than sitting in a depot over a weekend.

If a pen arrives damaged, warm, or not matching its certificate, contact us within 48 hours of delivery and we'll replace it.

Frequently Asked Questions

Is this the same thing as thymosin beta-4?

No. Thymosin beta-4 is a 43 amino acid protein. TB-500 is a synthetic seven amino acid fragment of it, containing the actin-binding region. They are often listed under the same name, which is worth knowing when comparing suppliers.

Is TB-500 prohibited in sport?

Yes. TB-500 appears on the World Anti-Doping Agency prohibited list. If you are a tested athlete, this is not a grey area.

Why is the solution clear rather than blue?

Blue solutions in our range are the copper complexes, GHK-Cu and AHK-Cu. TB-500 in solution is clear. Cloudiness or visible particles mean the pen should not be used.

Can I get TB-500 and BPC-157 in a single pen?

Yes. Our BPC-157 / TB-500 Stack holds 5mg of each in one solution. The trade-off is a fixed ratio, so if you need to vary the two independently, separate pens are the way.

How many doses are in a 5mg pen?

That depends entirely on the increment you dial, so there is no single answer. The counter shows what is set and the pen cannot be turned past the volume remaining.

Store at 2–8°C

Refrigerate on arrival and keep the pen in its carton, away from light.

Cold-chain shipped

Insulated packaging with a cold pack, in a plain outer box with no reference to the contents.

Never freeze

Freezing damages peptides held in solution. A frozen pen cannot be relied on afterwards.

Third-party tested

Every batch tested by an independent laboratory for identity and purity by HPLC.

Batch traceable

The batch number printed on the pen matches the number on its certificate.

Certificate on the page

Published exactly as the laboratory issued it. Not summarised, not on request.

OVERVIEW

Product Description

TB-500 is a synthetic peptide corresponding to the active fragment of thymosin beta-4. It is a short sequence rather than the full protein, which is the distinction worth checking when comparing listings, since the two are sometimes catalogued under the same name.

There is nothing to reconstitute. The compound arrives already dissolved at a known concentration, so there is no bacteriostatic water to add, no vial to swirl and no concentration to calculate. The dose is set on a mechanical counter that clicks as it turns, and the pen takes standard pen needles.

Every batch is tested by an independent laboratory before release. The certificate of analysis for this batch is published on this page and records identity, purity by HPLC and the date of testing. The batch number on the pen matches the batch number on the certificate.

Store refrigerated at 2–8°C and keep the pen in its carton, away from light. Do not freeze. Once the seal is broken, keep the pen refrigerated between uses and replace the cap after each use.

Ships in insulated packaging with a cold pack, in a plain outer box with no reference to the contents. Supplied for laboratory research use only. Not for human or veterinary use, and not a medicine.

Mechanism

How does it work

Thymosin beta-4’s best-understood property is that it binds to actin, a structural protein inside cells. By holding actin in its unassembled form, it influences how quickly cells can rebuild their internal scaffolding, which is part of how cells change shape and move.

TB-500 is the short section of that protein containing the actin-binding region, which is why it is studied as a stand-in for the whole molecule.

That is the mechanism as described in the literature. How much of it translates beyond the laboratory is not established, and we make no claim that it does.