PEG-MGF Pen
The MGF peptide with a polyethylene glycol chain attached. The chain adds bulk, which slows how fast the kidneys clear it. The peptide sequence itself is unchanged. This pen holds 2mg, already in solution.
Why it is being studiedPegylation. A standard method for extending how long a small peptide circulates.
Same sequence. The E domain peptide is unmodified; only the attachment is new.
Thin evidence base. Published work on the pegylated form specifically is limited.
Mostly preclinical research. Human data is limited, and nothing here establishes an effect in people.
£280.00
Before you start
Check the batch number on the pen against the certificate of analysis on this page. If they don't match, don't use the pen. Contact us and we'll replace it.
Inspect the solution through the window. It should be clear and free of particles. Copper peptide solutions are blue, and that colour is expected. Cloudiness, discolouration or visible matter means the pen should not be used.
The pen
Each pen arrives pre-filled, in solution, at the concentration on the label. There is nothing to reconstitute, no bacteriostatic water to add and no concentration to calculate.
The dose counter is mechanical. Turning the dial advances it one increment at a time, with an audible click per increment, and the number in the window is the amount set. The counter cannot be turned past the volume remaining.
Pens take standard pen needles, supplied with your order. Fit a fresh one each time and remove it afterwards. Leaving a needle attached lets air into the cartridge and can affect what the counter reads next.
Storage
Refrigerate at 2–8°C on arrival and keep the pen in its carton. Peptides in solution degrade faster in light, and copper peptides faster still.
Do not freeze. Freezing damages peptides in solution and the pen cannot be relied on afterwards, whatever it looks like.
Return the pen to refrigeration between uses once the seal is broken. A cold pen is stiffer to dial, so leaving it out for a few minutes beforehand makes the counter turn more smoothly.
Disposal
Used needles go into a sharps container, not household waste. UK pharmacies and local councils both supply them, and most councils collect full ones on request.
Supplied for laboratory research use only. Not for human or veterinary use, and not a medicine. Nothing on this page describes a protocol, a schedule or an application, and none should be inferred.
Every batch is tested before release
No batch reaches our shelves without a report from an independent laboratory. Testing is done by a third party with no commercial interest in the result, not by us and not by the manufacturer.
What the certificate shows
Identity, confirming the compound is what the label says it is. Purity, measured by high-performance liquid chromatography and reported as a percentage. The date of testing and the batch number the result applies to.
How to check it yourself
Every pen carries a batch number, and the certificate on this page carries the same number. If the two don't match, something has gone wrong in our dispatch and we want to hear about it. We'll replace the pen.
Certificates are published as the laboratory issued them. We don't retype results, summarise them or crop the report.
Cold chain
Stock is held refrigerated and ships in insulated packaging with a cold pack. Orders are dispatched so they travel over the shortest practical window rather than sitting in a depot over a weekend.
If a pen arrives damaged, warm, or not matching its certificate, contact us within 48 hours of delivery and we'll replace it.
Does pegylation change what the peptide does?
The sequence is unchanged, so the intended interaction is the same. What changes is how long it remains in circulation before being cleared.
Why is this pen 2mg when the MGF pen is 5mg?
The polyethylene glycol chain accounts for a large share of the mass of the pegylated molecule, so the same weight contains less of the peptide itself. The two are not directly comparable by milligram.
Is this prohibited in sport?
Yes. It appears on the World Anti-Doping Agency prohibited list. If you are a tested athlete, this is not a grey area.
Why is the solution clear rather than blue?
Blue solutions in our range are the copper complexes, GHK-Cu and AHK-Cu. This one in solution is clear. Cloudiness or visible particles mean the pen should not be used.
How many doses are in a 2mg pen?
That depends entirely on the increment you dial, so there is no single answer. The counter shows what is set and the pen cannot be turned past the volume remaining.
Store at 2–8°C
Refrigerate on arrival and keep the pen in its carton, away from light.
Cold-chain shipped
Insulated packaging with a cold pack, in a plain outer box with no reference to the contents.
Never freeze
Freezing damages peptides held in solution. A frozen pen cannot be relied on afterwards.
Third-party tested
Every batch tested by an independent laboratory for identity and purity by HPLC.
Batch traceable
The batch number printed on the pen matches the number on its certificate.
Certificate on the page
Published exactly as the laboratory issued it. Not summarised, not on request.
Product Description
PEG-MGF is the MGF peptide with polyethylene glycol attached. The PEG chain is part of the supplied molecule and is reflected in the certificate, so PEG-MGF and unmodified MGF are distinct products.
There is nothing to reconstitute. The compound arrives already dissolved at a known concentration, so there is no bacteriostatic water to add, no vial to swirl and no concentration to calculate. The dose is set on a mechanical counter that clicks as it turns, and the pen takes standard pen needles.
Every batch is tested by an independent laboratory before release. The certificate of analysis for this batch is published on this page and records identity, purity by HPLC and the date of testing. The batch number on the pen matches the batch number on the certificate.
Store refrigerated at 2–8°C and keep the pen in its carton, away from light. Do not freeze. Once the seal is broken, keep the pen refrigerated between uses and replace the cap after each use.
Ships in insulated packaging with a cold pack, in a plain outer box with no reference to the contents. Supplied for laboratory research use only. Not for human or veterinary use, and not a medicine.
How does it work
Polyethylene glycol chains are attached to small peptides to increase their effective size. Above a certain size the kidneys filter a molecule more slowly, so it stays in circulation longer. The approach is used across many licensed protein medicines.
Applied to MGF, the intent is to address the rapid clearance of the unmodified peptide. The binding partner for the E domain is still not clearly established, so what the extended exposure acts on remains an open question.
The published base here is small and much of it is preclinical. Nothing in it establishes an effect in people, and we make no claim that it does.
What’s included
- One pre-filled PEG-MGF pen, 2mg total content, supplied in solution
- Pen needles
- Storage and handling card
- Certificate of analysis, published on this page
- Insulated packaging with a cold pack
Specifications
- SKU
- NW-P-PEGMGF-2
- Format
- Pre-filled pen, in solution
- Total content
- 2mg
- Compounds
- PEG-MGF (pegylated mechano growth factor)
- Storage
- Refrigerate at 2–8°C
- Batch number
- NW-PMGF-260904-B
